Department of Chemistry and Physics

Dr. Krista R. Wilson

Dr. Krista R. Wilson

Associate Professor

226 Smith

704-233-8231

k.wilson@wingate.edu


Education
University of Florida, PhD
University of Florida, BS
Central Florida Community College, AA

About Me

I am an assistant professor in the Department of Chemistry and Physics at Wingate University. I got my bachelor’s degree in animal science with a minor in chemistry at the University of Florida, and my doctorate in medicinal chemistry at the University of Florida. My main research interests include peptide synthesis, specifically targeting the opioid receptors in the brain; synthetic microwave chemistry; and method development in peptide synthesis. I have three children, and my main interests involve reading, knitting and watching crime dramas.

Robyn Pescatore, Gina F. Marrone, Seth Sedberry, Daniel Vinton, Netanel Finkelstein, Yitzchak E. Katlowitz, Gavril W. Pasternak, Krista R. Wilson, Susruta Majumdar. “Synthesis and Pharmacology of Halogenated δ-Opioid-Selective [d-Ala(2)]Deltorphin II Peptide Analogues” ACS Chemical Neuroscience, 2015, 6(6): 905-910.

Patricia M. Hinkle, Madhavika N Serasinghe, Andrea Jakabowski, Julien A Sebag, Krista R Wilson, Carrie Haskell-Luevano. “Use of Chimeric Melanocortin-2 and -4 Receptors to Identify Regions Responsible for Ligand Specificity and Dependence on Melanocortin 2 Receptor Accessory Protein” European Journal of Pharmacology, 660 (2011) 94–102.

Wilson KR, Proneth B, Luesch H, Litherland SA, Haskell-Luevano C. “Construction and Characterization of Melanocortin-2 and -4 Receptor Chimeras.” Adv Exp Med Biol, 2009; 611:301-2.

Krista R. Wilson. “”Rational Approach to Design of Melanocortin Ligands and Receptor Chimeras.”” [Gainesville, Fla.] : University of Florida, 2008.

Joseph CG, Wilson KR, Wood MS, Sorenson NB, Phan DV, Xiang Z, Witek RM, Haskell-Luevano C. “The 1,4-benzodiazepine-2,5-dione small molecule template results in melanocortin receptor agonists with nanomolar potencies.” J Med Chem. 2008 Mar 13; 51(5):1423-31.

Katritzky AR, Khashab NM, Yoshioka M, Haase DN, Wilson KR, Johnson JV, Chung A, Haskell-Luevano C. “Microwave-assisted solid-phase peptide synthesis utilizing N-Fmoc-protected (alpha-aminoacyl)benzotriazoles.” Chem Biol Drug Des, 2007 Nov; 70(5):465-8.

Krista R. Wilson, Alexandar Todorovic, Bettina Proneth, Carrie Haskell-Luevano. “Overview Of Endogenous And Synthetic Melanocortin Peptides.” Cell and Molec. Biol. 2006, 2:3-20

Andrzej M. Wilczynski, Krista R. Wilson, Joseph W. Scott, Arthur S. Edison, and Carrie Haskell-Luevano. “Conformational Studies of AGRP-Melanocortin Chimeric Peptides.” APS manuscript In: Understanding Biology Using Peptides. Proc. of the 19th American Peptide Symposium; Ed. Blondelle, S.; American Peptide Society: San Diego, 2005: 381-382.

Krista R. Wilson, Andrzej M. Wilczynski, Joseph W. Scott, Rayna M. Bauzo, Carrie Haskell-Luevano. “Structure-Activity Studies of a Novel AGRP-Melanocortin Chimeric Template.”” APS manuscript In: Understanding Biology Using Peptides. Proc. of the 19th American Peptide Symposium; Ed. Blondelle, S.; American Peptide Society: San Diego, 2005: 521-522.

Andrzej Wilczynski, Krista R. Wilson, Joseph W. Scott, Arthur S. Edison and Carrie Haskell-Luevano. “Structure-Activity Relationships of the Unique and Potent Agouti Related Peptide (AGRP)-Melanocortin Chimeric Tyr-c[Asp-His-DPhe-Arg-Trp-Asn-Ala-Phe-Dpr]-Tyr-NH2 Peptide Template.” J. Med. Chem. 2005, 48:3060-3075.

Boman G. Irani, Jerry R. Holder, Aleksandar Todorovic, Andrzej M. Wilczynski, Christine G. Joseph, Krista R. Wilson, and Carrie Haskell-Luevano. “Progress in the Development of Melanocortin Receptor Selective Ligands.” Current Pharmaceutical Design, 2004, 10:3443-3479.

Krista R. Wilson, Robyn Pescatore, Gina F. Marrone, Seth Sedberry, Daniel Vinton, Netanel Finkelstein, Yitzchak E. Katlowitz, Gavril W. Pasternaka, J. Dylan McSwain, Susruta Majumdar. “Synthesis and Pharmacology of a Radioiodinated δ-opioid Selective Agonist Based on the [DAla2]Deltorphin II Template” American Peptide Symposium Poster Presentation, Orlando, FL, June 20-25, 2015.

Krista R. Wilson, Seth Sedberry, Robyn Pescatore, Sarah Ballard, Brian Love, Daniel Vinton, Eric Williamson. “Microwave-Assisted Cleavage of –Alloc and –OAllyl Protecting Groups in Solid Phase Peptide Synthesis.” American Peptide Symposium Poster Presentation, Orlando, FL, June 20-25, 2015.

“Synthesis and pharmacology of a δ-opioid selective [DAla-2] Deltorphin II peptide analog.” Southeastern Regional Meeting of the American Chemical Society Oral Presentation, October 16, 2014.

Seth Sedberry, Maggie I. Moore, Krista R. Wilson. “Microwave Deprotection of Boc-Protected Amino Acids Under Mildly Acidic Conditions.” Southeastern Regional Meeting of the American Chemical Society November 15, 2013.

Heather V. Clontz, Krista R. Wilson, Christopher E. Dahm. “A Model for a Sophomore Level Research Class.” Southeastern Regional Meeting of the American Chemical Society November 15, 2013.

Cody Flowers, Krista R. Wilson. “Microwave Synthesis of Cyclic δ-Opioid Peptides.” Wingate University Summer Research Oral Presentation. March 25, 2013.

Anna Wormsbecher, Krista R.Wilson. “Synthesis of δ-Opioid Selective Peptide Agonists with a Head-to-Side Chain Lactam Cyclization.” Wingate University Summer Research Oral Presentation, October 24, 2011.

Krista R. Wilson, Bettina Proneth, Hendrik Luesch, Sally A. Litherland, Carrie Haskell-Luevano. “Construction and Characterization of Human Melanocortin-2 and -4 Receptor Chimeras.” American Peptide Symposium, June 2007, Montreal, Quebec.

Krista R. Wilson, Michael Wood, Nick Sorenson, J. Ryan Holder, Zhimin Xiang, Fernanda Marques, Carrie Haskell-Luevano. “Cation-π Interactions are Involved in the Determination of Agonist and Antagonist Selectivity in Melanocortin Ligands.” University of Florida College of Pharmacy Symposium, February 2006, Gainesville, FL.

Andrzej Wilczynski, Krista R. Wilson, Joseph W. Scott, Arthur S. Edison, Carrie Haskell-Luevano. “Synthesis of AGRP-Melanocortin Chimeras.” American Peptide Symposium, June 2003, Boston, MA.

2017 Debra M. O’Neal Award for Excellence in Teaching

Undergraduate Research Mentor Award, Wingate University

2015 CEM Microwave-Enhanced Chemistry Grant, CEM Corporation

2012 Summer Research Grant, Wingate University

2011, 2012 Travel Grant, Wingate University

2010, 2011, 2012, 2013, 2014 University of Florida Alumni Fellowship

2003-2007 University of Florida College of Pharmacy Research Showcase Oral Competition Senior Division Winner

2007 University of Florida College of Pharmacy Research Showcase Oral Competition Junior Division Winner

2006 American Peptide Symposium Young Investigator’s Poster Competition Honorable Mention

2005 University of Florida College of Pharmacy Research Showcase Poster Competition Undergraduate Division Winner

2003 J. Wayne Reitz Union Award for Excellence

2003 Outstanding Graduating Senior in the College of Agriculture and Life Sciences